Antidepressants and Receptor Function

Released on by Ruth Porter
preview-18

  • Antidepressants and Receptor Function Book Detail

  • Author : Ruth Porter
  • Release Date : 2008-04-30
  • Publisher : John Wiley & Sons
  • Genre : Medical
  • Pages : 304
  • ISBN 13 : 0470513373
  • File Size : 57,57 MB
DOWNLOAD BOOK

Antidepressants and Receptor Function by Ruth Porter PDF Summary

Book Description: Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy, 1986 Depression is a common and often debilitating affective disorder. Attempts to develop effective antidepressants have a long history, but many questions remain about the mechanisms of action of such treatments and about the aetiology and pathophysiology of depression itself. Early observations centred attention on central monoamine systems, and animal studies suggested that changes in beta-adrenoceptor responsiveness were a common effect of antidepressant therapies. More recent research has encompassed many different central and peripheral receptors, time-dependent adaptational events at synapses, and the functional significance of changes in neurotransmitter systems in both humans and experimental animals. Such pharmacological studies aimed ultimately at elucidating the neurochemical basis of depression and of promoting new therapeutic approaches, provide the focus of this symposium volume. Many different methods of investigating the links between monoamine systems, depression and antidepressant treatments are described. Recent studies of receptors and of monoamine uptake sites in the brain and the periphery (e.g. in platelets and fibroblasts) are reviewed, with emphasis on alpha and beta adrenoceptors, [3H]imipramine-binding sites and serotonin receptors. The results of monitoring amine metabolites in cerebrospinal fluid and of measuring neuroendocrine, physiological and behavioural responses to pharmacological challenge are presented, providing information on monoaminergic function in depressed patients and experimental animals before, during and after treatment with antidepressant drugs or electroconvulsive shock. Genetic influences on receptor density are also discussed, as is the relevance to human depressive illness of animal models, including stress-induced behavioural depression in rats and responses to social stressors in rhesus monkeys. This book should be of interest to neuropharmacologists, psychopharmacologists, clinical pharmacologists, behavioural scientists, psychiatrists and neuroscientists.

Disclaimer: www.yourbookbest.com does not own Antidepressants and Receptor Function books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Antidepressants and Receptor Function

Antidepressants and Receptor Function

File Size : 21,21 MB
Total View : 8279 Views
DOWNLOAD

Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy, 1986 Depression is a common and often debilitating affective disord

Antidepressants

Antidepressants

File Size : 5,5 MB
Total View : 5483 Views
DOWNLOAD

This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depressi

Antidepressants

Antidepressants

File Size : 37,37 MB
Total View : 5464 Views
DOWNLOAD

Important clinical issues as the outcome of long term treatment with antidepressants, the time of onset of the antidepressant response and the limitations of th

Serotonin Receptors in Neurobiology

Serotonin Receptors in Neurobiology

File Size : 14,14 MB
Total View : 2482 Views
DOWNLOAD

A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subje

Antidepressants

Antidepressants

File Size : 9,9 MB
Total View : 3375 Views
DOWNLOAD

Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been arou