Applications of Domino Transformations in Organic Synthesis, Workbench Edition

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  • Applications of Domino Transformations in Organic Synthesis, Workbench Edition Book Detail

  • Author : Scott A. Snyder
  • Release Date : 2016-05-11
  • Publisher : Thieme Chemistry
  • Genre : Organic compounds
  • Pages : 0
  • ISBN 13 : 9783132401631
  • File Size : 91,91 MB

Applications of Domino Transformations in Organic Synthesis, Workbench Edition by Scott A. Snyder PDF Summary

Book Description: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. Science of Synthesis: Applications of Domino Transformations in Organic Synthesis explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds.

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