Autophagy in Health and Disease

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  • Autophagy in Health and Disease Book Detail

  • Author : Beverly Rothermel
  • Release Date : 2021-09-22
  • Publisher : Elsevier
  • Genre : Science
  • Pages : 456
  • ISBN 13 : 012822004X
  • File Size : 7,7 MB

Autophagy in Health and Disease by Beverly Rothermel PDF Summary

Book Description: Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspects, including stem cells, embryogenesis, hematopoiesis, and paligenosis. The subsequent sections are devoted to the role of autophagy in specific organ systems involved in metabolic control and diabetes (Chapters 12-15), the cardiovascular system (Chapters 16-18), and the nervous system (Chapters 19-20). The final section (Chapters 21-28) addresses autophagy in other organ systems vital to human health and longevity. Also included are chapters on microautophagy, chaperone-mediated autophagy, and the potential for autophagy as a therapeutic target.Autophagy in Health and Disease is invaluable to anyone new to the field as well as established investigators looking for a broader understanding of autophagy from outside their specific field of study. - Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathology - Offers extended coverage of the mechanisms that mediate autophagy - Covers the role of autophagy in stem cells and induced pluripotent stem cells, as well as the regenerative process of paligenosis - Highlights important questions that remain to be addressed

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Autophagy in Health and Disease

Autophagy in Health and Disease

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Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysio

Autophagy in Health and Disease

Autophagy in Health and Disease

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This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to

Exercise, Autophagy and Chronic Diseases

Exercise, Autophagy and Chronic Diseases

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This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the