PCR Mutation Detection Protocols

Released on by Bimal D. M. Theophilus
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  • PCR Mutation Detection Protocols Book Detail

  • Author : Bimal D. M. Theophilus
  • Release Date : 2008-02-02
  • Publisher : Springer Science & Business Media
  • Genre : Science
  • Pages : 214
  • ISBN 13 : 1592592732
  • File Size : 24,24 MB
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PCR Mutation Detection Protocols by Bimal D. M. Theophilus PDF Summary

Book Description: 1Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.

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