C-H Activation for Asymmetric Synthesis

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  • C-H Activation for Asymmetric Synthesis Book Detail

  • Author : Françoise Colobert
  • Release Date : 2019-11-12
  • Publisher : John Wiley & Sons
  • Genre : Science
  • Pages : 294
  • ISBN 13 : 3527343407
  • File Size : 52,52 MB

C-H Activation for Asymmetric Synthesis by Françoise Colobert PDF Summary

Book Description: Provides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry Written by leading international authors in the field, this book introduces readers to C-H activation in asymmetric synthesis along with all of its facets. It presents stereoselective C-H functionalization with a broad coverage, from outer-sphere to inner-sphere C-H bond activation, and from the control of olefin geometry to the induction of point, planar and axial chirality. Moreover, methods wherein asymmetry is introduced either during the C-H activation or in a different elementary step are discussed. Presented in two parts?asymmetric activation of C(sp3)-H bonds and stereoselective synthesis implying activation of C(sp2)-H bonds?CH-Activation for Asymmetric Synthesis showcases the diversity of stereogenic elements, which can now be constructed by C-H activation methods. Chapters in Part 1 cover: C(sp3)-H bond insertion by metal carbenoids and nitrenoids; stereoselective C-C bond and C-N bond forming reactions through C(sp3)?H bond insertion of metal nitrenoids; enantioselective intra- and intermolecular couplings; and more. Part 2 looks at: C-H activation involved in stereodiscriminant step; planar chirality; diastereoselective formation of alkenes through C(sp2)?H bond activation; amongst other methods. -Covers one of the most rapidly developing fields in organic synthesis and catalysis -Clearly structured in two parts (activation of sp3- and activation of sp2-H bonds) -Edited by two leading experts in C-H activation in asymmetric synthesis CH-Activation for Asymmetric Synthesis will be of high interest to chemists in academia, as well as those in the pharmaceutical and agrochemical industry.

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C-H Activation for Asymmetric Synthesis

C-H Activation for Asymmetric Synthesis

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Provides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry Written by leading international authors in the fiel

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C-H Activation for Asymmetric Synthesis

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Provides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry Written by leading international authors in the fiel

C-H Activation for Asymmetric Synthesis

C-H Activation for Asymmetric Synthesis

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Provides, in one handbook, comprehensive coverage of one of the hottest topics in stereoselective chemistry Written by leading international authors in the fiel

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Table of Contents - Synthesis in the Key of Catellani: Norbornene-Mediated ortho C–H Functionalization - Mechanistic Considerations in the Development and Use