Capsule Thermoregulation and Non-coding RNA in Streptococcus Pyogenes

Released on by Jordan Wright (‡e author)
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  • Capsule Thermoregulation and Non-coding RNA in Streptococcus Pyogenes Book Detail

  • Author : Jordan Wright (‡e author)
  • Release Date : 2014
  • Publisher :
  • Genre : Body temperature
  • Pages : 55
  • ISBN 13 :
  • File Size : 58,58 MB
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Capsule Thermoregulation and Non-coding RNA in Streptococcus Pyogenes by Jordan Wright (‡e author) PDF Summary

Book Description: Streptococcus pyogenes is a re-emerging pathogen that produces superficial and life threatening invasive diseases. One important virulence factor in S. pyogenes is hyaluronic acid capsule which has been shown to increase expression at sub-body temperatures in certain strains. This study showed that thermoregulation is common in invasive clinical isolates. Regulation was shown to occur independent of the CovRS two-component regulator in a post transcription manner and before protein level regulation. The endoribonuclease, CvfA, was also confirmed to be required for capsule thermoregulation. The search for a regulator lead to the discovery of the 1st antisense RNAs in S. pyogenes found opposite the capsule synthesis genes. Its role if any in capsule has not been discovered. Finally, a group of sRNAs were characterized adding to the knowledge of this layer of regulation in S. pyogenes.

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Bacterial Adhesion to Cells and Tissues

Bacterial Adhesion to Cells and Tissues

File Size : 63,63 MB
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Attachment to host cells or tissues is often the first step in the establishment of bacterial infections. A complex array of recognition, attachment, and virule