Carbohydrate Antigens As Tumor Markers

Released on by salwa AL-rubae
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  • Carbohydrate Antigens As Tumor Markers Book Detail

  • Author : salwa AL-rubae
  • Release Date : 2016-03-14
  • Publisher : Createspace Independent Publishing Platform
  • Genre :
  • Pages : 496
  • ISBN 13 : 9781530543267
  • File Size : 48,48 MB
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Carbohydrate Antigens As Tumor Markers by salwa AL-rubae PDF Summary

Book Description: This Book Deals with Determination of carbohydrate antigen 15-3 (CA15-3) and carbohydrate antigen 19-9 (CA 19-9) levels in sera of patients with benign and malignant breast tumors , Development of IRMA assay for the determination of CA15-3 and CA19-9 from cytosolic tissues of benign and malignant breast tumors ,Characterization of the binding of 125I-anti CA15-3 antibody with isolated human - CA15-3 in benign and malignant breast tumors, such as those of binding capacity and the effect of various factors (pH, temperature, time, halides, salts, CA15-3 and its antibody concentration) ,Determination of kinetic and thermodynamic parameters of the binding of partially purified CA15-3 with its specific antibody and Spectroscopic studies on (125I-anti CA15-3 antibody / CA15-3) complex in breast tissue . Further more the level of sera CA 15-3 in patients with benign and malignant breast tumors (preoperative) was measured by Immunoradiometric Assay (IRMA). Data analysis showed, concentrations of CA 15-3 were significantly higher in pre-and post-menopausal malignant breast tumors (P

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