Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

Released on by National Academies of Sciences, Engineering, and Medicine
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  • Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research Book Detail

  • Author : National Academies of Sciences, Engineering, and Medicine
  • Release Date : 2019-08-26
  • Publisher : National Academies Press
  • Genre : Science
  • Pages : 123
  • ISBN 13 : 0309488516
  • File Size : 83,83 MB
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Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research by National Academies of Sciences, Engineering, and Medicine PDF Summary

Book Description: The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

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Genome Editing in Neurosciences

Genome Editing in Neurosciences

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Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated