Cellular Mechanotransduction

Released on by Mohammad R. K. Mofrad
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  • Cellular Mechanotransduction Book Detail

  • Author : Mohammad R. K. Mofrad
  • Release Date : 2014-07-31
  • Publisher : Cambridge University Press
  • Genre : Technology & Engineering
  • Pages : 0
  • ISBN 13 : 9781107682467
  • File Size : 14,14 MB
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Cellular Mechanotransduction by Mohammad R. K. Mofrad PDF Summary

Book Description: "Mechanotransduction" is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

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An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—a