Chromatin Protocols

Released on by Peter B. Becker
preview-18

  • Chromatin Protocols Book Detail

  • Author : Peter B. Becker
  • Release Date : 2008-02-03
  • Publisher : Springer Science & Business Media
  • Genre : Science
  • Pages : 525
  • ISBN 13 : 1592596819
  • File Size : 74,74 MB
DOWNLOAD BOOK

Chromatin Protocols by Peter B. Becker PDF Summary

Book Description: More than 40 years after the discovery of the nucleosome as the fun- mental unit of chromatin, the multifaceted problem of how variations in ch- matin structure affect the activity of the eukaryotic genome has not been solved. However, during the past few years research on chromatin structure and fu- tion has gained considerable momentum, and impressive progress has been made at the level of concept development as well as filling in crucial detail. The structure of the nucleosome has been visualized at unprecedented reso- tion. Powerful multisubunit enzymes have been identified that alter histone/ DNA interactions in ways that expose regulatory sequences to factors initi- ing and regulating such nuclear processes as transcription. Though the imp- tance of posttranslational modifications of histones, notably their acetylation, has long been known, the finding that a number of bona fide regulators increase transcription by acetylating nucleosomes has lent new support to the old idea that the process of gene regulation is intimately related to the nature of the chromatin environment. A wealth of nonhistone proteins contribute to a continuum of structures with distinct biochemical properties and varying degrees of DNA condensation. Perhaps the most important conclusion from a large number of studies is a fresh appreciation of the dynamic nature of chromatin structure, the built-in flexibility providing the basis for regulation.

Disclaimer: www.yourbookbest.com does not own Chromatin Protocols books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Chromatin Protocols

Chromatin Protocols

File Size : 42,42 MB
Total View : 6558 Views
DOWNLOAD

More than 40 years after the discovery of the nucleosome as the fun- mental unit of chromatin, the multifaceted problem of how variations in ch- matin structure

Chromatin Protocols

Chromatin Protocols

File Size : 91,91 MB
Total View : 4090 Views
DOWNLOAD

Updated and revised, this thorough volume is organized such that it begins with techniques related to the study of chromatin structure. Protocols for reconstitu

RNA-Chromatin Interactions

RNA-Chromatin Interactions

File Size : 54,54 MB
Total View : 9232 Views
DOWNLOAD

This volume focuses on RNAs interacting with chromatin and their function. Chapters guide readers through transcription, splicing, non-coding RNA function and m

Chromatin Accessibility

Chromatin Accessibility

File Size : 29,29 MB
Total View : 1884 Views
DOWNLOAD

This detailed volume provides a comprehensive resource covering the existing and state-of-the-art tools in the field of profiling chromatin accessibility and it