Combinatorial Chemistry and Molecular Diversity in Drug Discovery

Released on by Eric M. Gordon
preview-18

  • Combinatorial Chemistry and Molecular Diversity in Drug Discovery Book Detail

  • Author : Eric M. Gordon
  • Release Date : 1998-08-27
  • Publisher : Wiley-Liss
  • Genre : Medical
  • Pages : 552
  • ISBN 13 :
  • File Size : 50,50 MB
DOWNLOAD BOOK

Combinatorial Chemistry and Molecular Diversity in Drug Discovery by Eric M. Gordon PDF Summary

Book Description: Increasing pressure to identify, optimize, develop, and commercialize novel drugs more rapidly and more cost-effectively has led to an urgent demand for technologies that can reduce the time to market for new products. Molecular diversity, of both natural and synthetic materials, provides a valuable source of compounds for identifying and optimizing new drug leads. Through the rapidly evolving technology of combinatorial chemistry, it is now possible to produce libraries of small molecules to screen for novel bioactivities. This powerful new technology has begun to help pharmaceutical companies find new drug candidates quickly, save significant dollars in preclinical development costs, and ultimately change their fundamental approach to drug discovery. Included among the many topics: Historical background. Library strategy and design. Solid-phase synthesis. Small molecular libraries. Automation, analytical, and computational methodology. Biological diversity. Strategies for screening combinatorial libraries. Combinatorial drug screening and development. Combinatorial chemistry information management.

Disclaimer: www.yourbookbest.com does not own Combinatorial Chemistry and Molecular Diversity in Drug Discovery books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Molecular Diversity in Drug Design

Molecular Diversity in Drug Design

File Size : 43,43 MB
Total View : 3016 Views
DOWNLOAD

High-throughput screening and combinatorial chemistry are two of the most potent weapons ever to have been used in the discovery of new drugs. At a stroke, it s