Complement and Kidney Disease

preview-18
  • Complement and Kidney Disease Book Detail

  • Author : Peter F Zipfel
  • Release Date : 2005-12-09
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 264
  • ISBN 13 : 9783764371661
  • File Size : 23,23 MB

Complement and Kidney Disease by Peter F Zipfel PDF Summary

Book Description: The understanding how complement relates to glomerular diseases has evolved considerably during the last years. Substantial evidence has accumulated that explain how a defective or deregulated complement system results in kidney diseases. The combination and close interaction of basic research with clinical medicine has demonstrated an important role of complement effector and regulatory proteins in pathological settings of the kidney. A large panel of distinct human kidney diseases such as hemolytic uremic syndrome (HUS), membrano proliferative glomerulonephritis (MPGN), systemic lupus erythematosus (SLE) and in ischemic reperfusions injury and transplantation are caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms already allowed to establish new diagnostic and novel promising therapeutic approaches for several human kidney diseases.

Disclaimer: www.yourbookbest.com does not own Complement and Kidney Disease books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Complement and Kidney Disease

Complement and Kidney Disease

File Size : 75,75 MB
Total View : 9858 Views
DOWNLOAD

The understanding how complement relates to glomerular diseases has evolved considerably during the last years. Substantial evidence has accumulated that explai

Complement and Kidney Disease

Complement and Kidney Disease

File Size : 93,93 MB
Total View : 5448 Views
DOWNLOAD

The understanding how complement relates to glomerular diseases has evolved considerably during the last years. Substantial evidence has accumulated that explai

Pediatric Kidney Disease

Pediatric Kidney Disease

File Size : 44,44 MB
Total View : 3171 Views
DOWNLOAD

The new edition of this valuable clinical resource offers a state of the art, comprehensive review on every clinical condition encountered in pediatric nephrolo

Silva's Diagnostic Renal Pathology

Silva's Diagnostic Renal Pathology

File Size : 27,27 MB
Total View : 5374 Views
DOWNLOAD

An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

IgG4-Related Kidney Disease

IgG4-Related Kidney Disease

File Size : 42,42 MB
Total View : 8604 Views
DOWNLOAD

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related dis