CRISPR-Cas System Based Diagnosis of Infectious Diseases

Released on by Roohi Bansal
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  • CRISPR-Cas System Based Diagnosis of Infectious Diseases Book Detail

  • Author : Roohi Bansal
  • Release Date : 2021-03-08
  • Publisher :
  • Genre :
  • Pages : 214
  • ISBN 13 : 9789354458309
  • File Size : 27,27 MB
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CRISPR-Cas System Based Diagnosis of Infectious Diseases by Roohi Bansal PDF Summary

Book Description: Since its discovery as a part of the bacterial defense mechanism, the Nobel Prize-winning technology CRISPR-Cas system has revolutionized the fields of genome editing and genetic engineering. Beyond gene-editing ability, scientists have leveraged its potential in the diagnosis of infectious diseases including COVID-19. This book provides a detailed understanding of CRISPR-based rapid and point-of-care diagnostic kits like SHERLOCK, DETECTR, FELUDA, AIOD CRISPR-Cas12a, etc. for the diagnosis of infectious diseases including COVID-19; the importance of isothermal nucleic acid amplification processes like RPA and LAMP; and how the results of the CRISPR-based tests can be interpreted using paper-based lateral flow strips. Because of the ease of performing the test and simple interpretation of the test results, CRISPR-based tests can be used at airports, ports, clinics, schools, etc., for better disease diagnosis, monitoring, management, and containment of infectious diseases like COVID-19. Additionally, this book discusses Monoclonal Antibodies, which have revolutionized the treatment for cancer, arthritis, autoimmune diseases, etc. This book also talks about various strategies to isolate monoclonal antibodies from the COVID-19 recovered people and different ways to engineer these antibodies using hybridoma technology.

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