Design, Analysis, and Interpretation of Genome-Wide Association Scans

Released on by Daniel O. Stram
preview-18

  • Design, Analysis, and Interpretation of Genome-Wide Association Scans Book Detail

  • Author : Daniel O. Stram
  • Release Date : 2013-11-23
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 344
  • ISBN 13 : 1461494435
  • File Size : 64,64 MB
DOWNLOAD BOOK

Design, Analysis, and Interpretation of Genome-Wide Association Scans by Daniel O. Stram PDF Summary

Book Description: This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects. Particular detail is given to the practical aspects of employing the bioinformatics and data handling methods necessary to prepare data for statistical analysis. The goal in writing this book is to give statisticians, epidemiologists, and students in these fields the tools to design a powerful genome-wide study based on current technology. The other part of this is showing readers how to conduct analysis of the created study. Design and Analysis of Genome-Wide Association Studies provides a compendium of well-established statistical methods based upon single SNP associations. It also provides an introduction to more advanced statistical methods and issues. Knowing that technology, for instance large scale SNP arrays, is quickly changing, this text has significant lessons for future use with sequencing data. Emphasis on statistical concepts that apply to the problem of finding disease associations irrespective of the technology ensures its future applications. The author includes current bioinformatics tools while outlining the tools that will be required for use with extensive databases from future large scale sequencing projects. The author includes current bioinformatics tools while outlining additional issues and needs arising from the extensive databases from future large scale sequencing projects.

Disclaimer: www.yourbookbest.com does not own Design, Analysis, and Interpretation of Genome-Wide Association Scans books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Handbook of Statistical Genomics

Handbook of Statistical Genomics

File Size : 89,89 MB
Total View : 6241 Views
DOWNLOAD

A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statisti

Stroke Genetics

Stroke Genetics

File Size : 43,43 MB
Total View : 2347 Views
DOWNLOAD

Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, resear