Detecting Prompt Gammas as a Means of Dosimetry and Range Verification Measurements for Treatment Validation of High-energy Beams in PBT

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  • Detecting Prompt Gammas as a Means of Dosimetry and Range Verification Measurements for Treatment Validation of High-energy Beams in PBT Book Detail

  • Author : Laura Harkness-Brennan
  • Release Date : 2017
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  • File Size : 41,41 MB
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Detecting Prompt Gammas as a Means of Dosimetry and Range Verification Measurements for Treatment Validation of High-energy Beams in PBT by Laura Harkness-Brennan PDF Summary

Book Description: Protons are used in radiation therapy of cancerous tissue as they have the potential benefit of sparing dose to healthy tissue, due to manipulation of the positioning of the Bragg Peak as a function of depth in the body[1]. However, there is a need for a more precise method for range verification and the monitoring of dose delivery in real-time[2]. The University of Liverpool have developed the prompt-gamma imaging (GRI+) system, to measure the prompt gamma rays emitted and therefore the dose distribution of the proton beam during proton therapy. The GRI+ system is composed of a triple-layer semiconductor Compton camera (two position-sensitive scatter detectors and an absorber detector). The prompt gamma rays can deposit their energy across the detector system in a large variety of sequences. The systemu2019s performance has so far been investigated using the simplest event sequence, which is a single interaction event in each detector. In this case, a spatial image resolution of around 5 mm was determined. However, for high photon energies, such as those observed in proton therapy, multiple interaction events are probable. In this study, the effective use of multiple interaction events will be discussed. The poster will also outline plans for an experiment to be conducted at the Clatterbridge Cancer Centre, UK, as part of the next phase of the project.

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Practical Gamma-ray Spectrometry

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The cutting-edge new edition of the classic introduction to radioactive measurement Gammy-Ray Spectrometry is a key technique in the study of radioactive decay.