DNA polymerases in Biotechnology

Released on by Zvi Kelman
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  • DNA polymerases in Biotechnology Book Detail

  • Author : Zvi Kelman
  • Release Date : 2015-03-18
  • Publisher : Frontiers Media SA
  • Genre : Biotechnology
  • Pages : 147
  • ISBN 13 : 2889194558
  • File Size : 45,45 MB
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DNA polymerases in Biotechnology by Zvi Kelman PDF Summary

Book Description: DNA polymerases are core tools for molecular biology including PCR, whole genome amplification, DNA sequencing and genotyping. Research has focused on discovery of novel DNA polymerases, characterization of DNA polymerase biochemistry and development of new replication assays. These studies have accelerated DNA polymerase engineering for biotechnology. For example, DNA polymerases have been engineered for increased speed and fidelity in PCR while lowering amplification sequence bias. Inhibitor resistant DNA polymerase variants enable PCR directly from tissue (i.e. blood). Design of DNA polymerases that efficiently incorporate modified nucleotide have been critical for development of next generation DNA sequencing, synthetic biology and other labeling and detection technologies. The Frontiers in Microbiology Research Topic on DNA polymerases in Biotechnology aims to capture current research on DNA polymerases and their use in emerging technologies.

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DNA polymerases in Biotechnology

DNA polymerases in Biotechnology

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DNA polymerases are core tools for molecular biology including PCR, whole genome amplification, DNA sequencing and genotyping. Research has focused on discovery

DNA Polymerases

DNA Polymerases

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Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that main