Emerging Learnings in Cell Therapy: Novel Binding Domains, Universal CAR-T Cells, and More

Released on by Anand Rotte
preview-18

  • Emerging Learnings in Cell Therapy: Novel Binding Domains, Universal CAR-T Cells, and More Book Detail

  • Author : Anand Rotte
  • Release Date : 2024-04-22
  • Publisher : Frontiers Media SA
  • Genre : Medical
  • Pages : 129
  • ISBN 13 : 2832548326
  • File Size : 19,19 MB
DOWNLOAD BOOK

Emerging Learnings in Cell Therapy: Novel Binding Domains, Universal CAR-T Cells, and More by Anand Rotte PDF Summary

Book Description: The Past decade has seen significant advances in cancer immunotherapy with the development of multiple strategies including monoclonal antibodies targeting checkpoint blockers, oncolytic viruses, fusion proteins and cell therapies such as tumor-specific chimeric antigen receptor (CAR-) T cell therapy, NK cell therapy and γδ-T-cell therapy. Multiple cell therapies including sipuleucel-T (Provange), axicabtagene ciloleucel (Yescarta), brexucabtagene autoleucel (Tecartus), tisagenlecleucel (Kymriah), lisocabtagene maraleucel (Breyanzi), idecabtagene vicleucel (Abecma) and ciltacabtagene autoleucel (Carvykti) have been approved by the US FDA for different hematological cancers and hormone-refractory prostate cancer (Provange). Impressive results were noted with CAR-T cell therapy with objective response rates (ORR) as high as 100% in certain hematological cancers and with responses durable over 10 years in some patients.

Disclaimer: www.yourbookbest.com does not own Emerging Learnings in Cell Therapy: Novel Binding Domains, Universal CAR-T Cells, and More books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Cell and Gene Therapies

Cell and Gene Therapies

File Size : 22,22 MB
Total View : 514 Views
DOWNLOAD

In this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and g