European Surveillance of Clostridioides (Clostridium) Difficile Infections

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  • European Surveillance of Clostridioides (Clostridium) Difficile Infections Book Detail

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  • Release Date : 2019
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  • ISBN 13 : 9789294984500
  • File Size : 31,31 MB
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European Surveillance of Clostridioides (Clostridium) Difficile Infections by PDF Summary

Book Description: In response to the emerging problems with Clostridioides (Clostridium) difficile infections (CDIs), the European Centre for Disease Prevention and Control (ECDC) in collaboration with the US Centers for Disease Control and Prevention (CDC), published background information about the changing epidemiology of CDIs, agreed on CDI case-definitions and issued recommendations for the surveillance of CDIs. An ECDC-funded survey performed in 2008 revealed a mean incidence of 4.1 per 10 000 patient-days per hospital (range: 0.0-36.3), almost 70% higher than that reported in a previous European surveillance study performed in 2005 (2.45 per 10 000 patient-days per hospital, range: 0.13-7.1), although each survey had a different design. Standardised periodic or continuous surveillance of the incidence of CDI is more likely to facilitate the identification of epidemiological changes and is an essential tool for CDI prevention and control. Microbiological data supplements surveillance data, allowing further insights into epidemiological changes. Facing the lack of standardised surveillance of CDI in EU/EEA countries, ECDC launched a call for tender to support capacity building for surveillance of CDIs at the European level in 2010. The contract was awarded to a consortium that carried out the European Clostridium difficile Surveillance Network (ECDIS-Net) project from 20 December 2010 to 30 November 2014. The ECDIS-Net project developed a protocol for the surveillance of CDI, which was pilot tested in 37 hospitals in 14 countries in 2013. This protocol (version 2.4) incorporates feedback from countries and hospitals that participated in the pilot survey, feedback from the final meeting of the ECDIS-Net project, as well as discussion with the ESCMID Study Group for C. difficile (ESCGD) to obtain information about its draft and final versions of the ESCMID guidelines 'Update of the diagnostic guidance document for Clostridium difficile infection' and 'Guidance document for prevention of Clostridium difficile infection in acute healthcare settings'. On 1 January 2016, ECDC started the coordination of surveillance of CDI in acute care hospitals in EU/EEA countries, with data reported to ECDC annually. During a 'start-up wave', EU/EEA countries were encouraged to recruit at least one hospital to participate for at least one month between January and March 2016. At least 20 countries participated in this first phase, with the majority continuing data collection throughout 2016. The CDI surveillance data for 2016 are reported in the ECDC Annual Epidemiological Report, available on the ECDC website, including its webpage dedicated to ECDC CDI activities. ECDC will coordinate another wave of participation in October-December 2020. In this second phase, countries that do not participate in European CDI surveillance are encouraged to recruit at least one hospital for at least one month; and countries that do participate are encouraged to recruit additional hospitals for at least one month (recommended three months). ECDC is also working with countries with national CDI surveillance that are compatible with this protocol to convert their national dataset into a compatible format for joint analyses. Those seeking further information about options to participate should contact their National Focal Point for Healthcare- Associated Infections in their country.

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Updates on Clostridium difficile in Europe

Updates on Clostridium difficile in Europe

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This book outlines the currently available clinical, epidemiological and experimental data on Clostridium difficile infection (CDI) with special emphasis on stu