Evolutionarily Conserved Cytotoxic T-Lymphocyte Epitopes on the Human Immunodeficiency Virus and the Feline Immunodeficiency Virus for an HIV-1 Vaccine

Released on by Missa P. Sanou
preview-18

  • Evolutionarily Conserved Cytotoxic T-Lymphocyte Epitopes on the Human Immunodeficiency Virus and the Feline Immunodeficiency Virus for an HIV-1 Vaccine Book Detail

  • Author : Missa P. Sanou
  • Release Date : 2012
  • Publisher :
  • Genre :
  • Pages : 104
  • ISBN 13 :
  • File Size : 45,45 MB
DOWNLOAD BOOK

Evolutionarily Conserved Cytotoxic T-Lymphocyte Epitopes on the Human Immunodeficiency Virus and the Feline Immunodeficiency Virus for an HIV-1 Vaccine by Missa P. Sanou PDF Summary

Book Description: The current studies identified conserved regions on HIV by simultaneously comparing the immunological responses of HIV-infected individuals to overlapping peptides from HIV and from the feline immunodeficiency virus (FIV). The reverse transcriptase enzymes and viral core capsid proteins of both HIV and FIV were evaluated for their counterpart conserved CTL epitopes. These studies showed that the proliferation profile of T cells to HIV and FIV may be more useful for the identification of conserved regions than their induction of interferon-gamma secretion. Furthermore, the current approach was able to identify a unique HIV-specific epitope, never described before which is highly conserved among lentiviruses and which has the ability to induce CTL cytokines. Therefore, evolutionarily-conserved HIV CTL epitopes exist and can be mapped by comparing the immunological responses of HIV-infected subjects to the conserved proteins between HIV and FIV, and possibly other lentiviruses.

Disclaimer: www.yourbookbest.com does not own Evolutionarily Conserved Cytotoxic T-Lymphocyte Epitopes on the Human Immunodeficiency Virus and the Feline Immunodeficiency Virus for an HIV-1 Vaccine books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.