Frontiers in Protein Structure, Function, and Dynamics

Released on by Dev Bukhsh Singh
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  • Frontiers in Protein Structure, Function, and Dynamics Book Detail

  • Author : Dev Bukhsh Singh
  • Release Date : 2020-07-02
  • Publisher : Springer Nature
  • Genre : Science
  • Pages : 458
  • ISBN 13 : 9811555303
  • File Size : 40,40 MB
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Frontiers in Protein Structure, Function, and Dynamics by Dev Bukhsh Singh PDF Summary

Book Description: This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.

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This volume is a collection of articles from the proceedings of the International School of Structural Biology and Magnetic Resonance 3rd Course: Protein Dynami

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Proteins

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The major goal of 'Expanding Frontiers in Polypeptide and Protein Structural Research' has been to bring the various avenues for the exploration of protein stru