Genomic Elements in Health, Disease and Evolution

Released on by Kyriacos Felekkis
preview-18

  • Genomic Elements in Health, Disease and Evolution Book Detail

  • Author : Kyriacos Felekkis
  • Release Date : 2015-09-30
  • Publisher : Springer
  • Genre : Medical
  • Pages : 319
  • ISBN 13 : 1493930702
  • File Size : 5,5 MB
DOWNLOAD BOOK

Genomic Elements in Health, Disease and Evolution by Kyriacos Felekkis PDF Summary

Book Description: Over 98% of the human genome contains non-coding DNA sequences. For many years molecular biologists referred to this component of the genome as the “junk” DNA since it does not code for any “useful” protein product. Over the last years this notion changed significantly as scientists discovered that a large part of this DNA contains various genomic elements that have important roles in cell physiology. Genomic elements such as non-coding RNAs, transposons, splicing RNAs, DNA repeats and others were shown to play a significant role in regulating gene expression. In addition, all these elements were implicated to contribute in the pathogenesis or progression of various human diseases. In this book, the editor will attempt to describe all these genomic elements that constitute the junk DNA of the genome. For every genomic element, the physiologic role in the organism, its role in evolution and any possible involvement in human diseases will be discussed. Additionally, interaction between these elements in normal or pathologic condition will be discussed. Since a large amount of new knowledge is generated daily in regards to these genomic elements, this book will attempt to combine all the information in a single publication that can serve as a reference for future studies. The first part will discuss RNA elements such as microRNAs, long non-coding RNAs, piRNAs and splicing RNAs. The second part of the book will deal with transposons, retrotransposons and DNA transposons. Finally the third part of the book will discuss DNA elements that include DNA repeats, conserved non-coding sequences, distal genomic elements, introns, pseudogenes, CpG islands and telomeres. For miRNAs and CNVs a separate chapter will be dedicated to their role in human diseases since an extensive amount of information exists about these two elements.

Disclaimer: www.yourbookbest.com does not own Genomic Elements in Health, Disease and Evolution books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Genomes, Evolution, and Culture

Genomes, Evolution, and Culture

File Size : 28,28 MB
Total View : 9374 Views
DOWNLOAD

This book combines recent information and discoveries in the field of human molecular biology and human molecular evolution. It provides an interdisciplinary ap

Evolution of the Human Genome I

Evolution of the Human Genome I

File Size : 83,83 MB
Total View : 9287 Views
DOWNLOAD

This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes

Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome

File Size : 90,90 MB
Total View : 7124 Views
DOWNLOAD

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-r