Glycosylation Engineering of Biopharmaceuticals

Released on by Alan Beck
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  • Glycosylation Engineering of Biopharmaceuticals Book Detail

  • Author : Alan Beck
  • Release Date : 2013-03-09
  • Publisher : Humana Press
  • Genre : Medical
  • Pages : 0
  • ISBN 13 : 9781627033268
  • File Size : 29,29 MB
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Glycosylation Engineering of Biopharmaceuticals by Alan Beck PDF Summary

Book Description: Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.

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Conceived with the intention of providing an array of strategies and technologies currently in use for glyco-engineering distinct living organisms, this book co

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The analysis and modification of glycans of recombinant proteins continues to be active and challenging area of research and for the successful manufacture of t