Guide to Mutation Detection

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  • Guide to Mutation Detection Book Detail

  • Author : Human Genome Organisation
  • Release Date : 2005-02-03
  • Publisher : John Wiley & Sons
  • Genre : Science
  • Pages : 348
  • ISBN 13 :
  • File Size : 79,79 MB

Guide to Mutation Detection by Human Genome Organisation PDF Summary

Book Description: Guide to both the theory and practice of mutation detection technology, including detailed practical protocols that are derived from courses run by the Human Genome Organization (HUGO). Guide to Mutation Detection offers the only single source for assessing the molecular biological tools for mutation analysis in order to design an experiment. The first section reviews topics such as key technologies, mutation scanning, cleavage, quality control, high throughput approaches, databases, and nomenclature. The second part covers step-by-step protocols and discussion of methods such as tag-array minisequencing, electronic hybridization, pyrosequencing, fluorescent SSCP, DHPLC, array CGH, and MADGE.

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Cancer and the mechanisms of its development are receiving increasing research interest. This is the first single author book describing and reviewing mutation