Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

Released on by Guido Kroemer
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  • Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism Book Detail

  • Author : Guido Kroemer
  • Release Date : 2014
  • Publisher : Academic Press
  • Genre : HEALTH & FITNESS
  • Pages : 509
  • ISBN 13 : 9780124166189
  • File Size : 75,75 MB
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Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism by Guido Kroemer PDF Summary

Book Description: Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Provides theoretical overview on metabolic alterations of cancer cells, and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo

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