Mouse Models of Human Cancer PDF book is popular Science book written by Eric C. Holland. The book was released by John Wiley & Sons on 2004-08-27 with total hardcover pages 504. Fast download link is given in this page, you could read Mouse Models of Human Cancer by Eric C. Holland in PDF, epub and kindle directly from your devices.
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are ab
Mice have become the species of choice for modeling the complex interactions between tumor cells and the host environment. Mouse genetics are easily manipulated
Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an i
p53 has emerged as a key tumor suppressor and important target for novel cancer therapy. This book, written by world-leading p53 researchers including many of t
This project follows on the success of the book "25 years of p53", published by Springer in 2006. Since this publication, there have been considerable advances
