Histone Deacetylase Inhibitors - Epidrugs for Neurological Disorders

Released on by Shabir Ahmad Ganai
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  • Histone Deacetylase Inhibitors - Epidrugs for Neurological Disorders Book Detail

  • Author : Shabir Ahmad Ganai
  • Release Date : 2019
  • Publisher :
  • Genre : Biochemistry
  • Pages : 93
  • ISBN 13 : 9789811380204
  • File Size : 97,97 MB
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Histone Deacetylase Inhibitors - Epidrugs for Neurological Disorders by Shabir Ahmad Ganai PDF Summary

Book Description: This book provides an outline of epigenetics as a whole, while also specifically examining a range of epigenetic players, including histone acetyl transferases (HATs) and histone deacetylases (HDACs). It chiefly focuses on the emerging targets of HDACs and their implications for various neurological disorders, while also discussing the drawbacks of current therapeutic strategies, the classification of HDAC inhibitors, and their promising effects in connection with specific neurological disorders. The book explores the potential use of these inhibitors as novel therapeutic agents, considers the current challenges involved in using them to tackle neurological complications, and offers a novel solution by designing isoform-selective inhibitors and employing combinatorial therapeutic strategies. Its final section, which explores future directions, elaborates on the possibility of enhancing HDAC inhibitors' therapeutic efficacy against various neurological complications.

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Neuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics

File Size : 69,69 MB
Total View : 6084 Views
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Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume