Histone Modifications in Therapy

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  • Histone Modifications in Therapy Book Detail

  • Author : Pedro Castelo-Branco
  • Release Date : 2020-09-04
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 490
  • ISBN 13 : 0128164220
  • File Size : 20,20 MB

Histone Modifications in Therapy by Pedro Castelo-Branco PDF Summary

Book Description: Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and inflammatory disorders, among others. In relation to these disease types, histone modifications are discussed, both as mechanisms of prevention and possible treatment. A concluding chapter brings together future perspectives for targeting histone modifications in therapy and next steps in research. Examines the use of histone modifications in disease prevention and therapy Explores the role of histone modifications in cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, and inflammatory disease, among others Features chapters from a broad range of international authors and disease specialists

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Histone Modifications in Therapy

Histone Modifications in Therapy

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Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifica

Histone Modifications in Therapy

Histone Modifications in Therapy

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Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifica

The Histone Code and Beyond

The Histone Code and Beyond

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Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquit

The Histone Code and Beyond

The Histone Code and Beyond

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Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquit

Epigenetic Mechanisms of Gene Regulation

Epigenetic Mechanisms of Gene Regulation

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Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in m