Human Dna Polymerases: Biology, Medicine And Biotechnology

Released on by Giovanni Maga
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  • Human Dna Polymerases: Biology, Medicine And Biotechnology Book Detail

  • Author : Giovanni Maga
  • Release Date : 2017-11-10
  • Publisher : World Scientific
  • Genre : Science
  • Pages : 398
  • ISBN 13 : 9813226420
  • File Size : 36,36 MB
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Human Dna Polymerases: Biology, Medicine And Biotechnology by Giovanni Maga PDF Summary

Book Description: Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, next generation sequencing, nucleic acids based diagnostics and in techniques to analyze ancient and otherwise damaged DNA (e.g. for forensic applications). Moreover, some diseases are related to DNA polymerase defects and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes.

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