Identification of Internal Kinesin Regions Necessary for Microtubule Depolymerization

Released on by Krista M. Shipley
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  • Identification of Internal Kinesin Regions Necessary for Microtubule Depolymerization Book Detail

  • Author : Krista M. Shipley
  • Release Date : 2006
  • Publisher :
  • Genre :
  • Pages : 296
  • ISBN 13 :
  • File Size : 42,42 MB
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Identification of Internal Kinesin Regions Necessary for Microtubule Depolymerization by Krista M. Shipley PDF Summary

Book Description: Internal kinesins (KinI), which depolymerize microtubules instead of walking on them, are an interesting example of adapted evolution. Although they have extensions from the motor core at both the N- and C-termini (hence the name "Internal"), the motor core alone is sufficient for some depolymerization activity. Addition of the 50 amino-acid N-terminal "neck" to the motor core is enough to restore activity near that of the full-length protein, probably by helping the protein to localize to the microtubule ends.

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