Ion Channels and Disease

Released on by Frances M. Ashcroft
preview-18

  • Ion Channels and Disease Book Detail

  • Author : Frances M. Ashcroft
  • Release Date : 1999-10-20
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 505
  • ISBN 13 : 0080535216
  • File Size : 60,60 MB
DOWNLOAD BOOK

Ion Channels and Disease by Frances M. Ashcroft PDF Summary

Book Description: Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. Introduces the relevant aspects of molecular biology and biophysics Describes the principal methods used to study channelopathies Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype

Disclaimer: www.yourbookbest.com does not own Ion Channels and Disease books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Ion Channels and Disease

Ion Channels and Disease

File Size : 30,30 MB
Total View : 7555 Views
DOWNLOAD

Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all

Ion Channel Diseases

Ion Channel Diseases

File Size : 20,20 MB
Total View : 7630 Views
DOWNLOAD

Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain.

Channelopathies

Channelopathies

File Size : 50,50 MB
Total View : 2878 Views
DOWNLOAD

This book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology,

Handbook of Ion Channels

Handbook of Ion Channels

File Size : 83,83 MB
Total View : 9437 Views
DOWNLOAD

The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate

Ion Channels in Health and Disease

Ion Channels in Health and Disease

File Size : 78,78 MB
Total View : 9099 Views
DOWNLOAD

Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates di