Oxidative Stress and Vascular Disease

Released on by John F. Keaney Jr.
preview-18

  • Oxidative Stress and Vascular Disease Book Detail

  • Author : John F. Keaney Jr.
  • Release Date : 2012-12-06
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 404
  • ISBN 13 : 1461546494
  • File Size : 98,98 MB
DOWNLOAD BOOK

Oxidative Stress and Vascular Disease by John F. Keaney Jr. PDF Summary

Book Description: One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.

Disclaimer: www.yourbookbest.com does not own Oxidative Stress and Vascular Disease books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Oxidative Stress and Vascular Disease

Oxidative Stress and Vascular Disease

File Size : 79,79 MB
Total View : 1761 Views
DOWNLOAD

One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atheros

Antioxidants and Cardiovascular Disease

Antioxidants and Cardiovascular Disease

File Size : 25,25 MB
Total View : 470 Views
DOWNLOAD

Generation of oxidants or reactive oxygen species is a natural process of human biology. Mitochondrial respiration, phagocytic activity and cyclooxygenase activ

Doctoring

Doctoring

File Size : 12,12 MB
Total View : 4996 Views
DOWNLOAD

American medicine attracts some of the brightest and most motivated people the country has to offer, and it boasts the most advanced medical technology in the w

Doctoring

Doctoring

File Size : 72,72 MB
Total View : 3287 Views
DOWNLOAD

Addressing the problems facing medicine and medical education Cassell discusses the new generalism and the skills that physicians-in-training must be taught in

Molecular Mechanisms of Atherosclerosis

Molecular Mechanisms of Atherosclerosis

File Size : 19,19 MB
Total View : 5945 Views
DOWNLOAD

Atherosclerosis is the most common cardiovascular disorder in western societies and is rapidly becoming similarly prevalent in the underdeveloped world. Written