Chemokine Receptors as Drug Targets

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  • Chemokine Receptors as Drug Targets Book Detail

  • Author : Martine J. Smit
  • Release Date : 2010-12-07
  • Publisher : John Wiley & Sons
  • Genre : Medical
  • Pages : 598
  • ISBN 13 : 3527632344
  • File Size : 86,86 MB

Chemokine Receptors as Drug Targets by Martine J. Smit PDF Summary

Book Description: Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development of innovative drugs against AIDS, cancer, neural and autoimmune diseases. Here is the first reference focusing on these novel drug development opportunities. Opening with a general introduction on chemokine function and chemokine receptor biology, the second part covers the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including AIDS. The third part systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to-date reports from the pharmaceutical industry.

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Chemokine Receptors as Drug Targets

Chemokine Receptors as Drug Targets

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Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine resea

Chemokines

Chemokines

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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art

Chemokines, Part A

Chemokines, Part A

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The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a w