Mechanisms of Stimulus—Response Coupling in Platelets

Released on by J. Westwick
preview-18

  • Mechanisms of Stimulus—Response Coupling in Platelets Book Detail

  • Author : J. Westwick
  • Release Date : 2013-03-09
  • Publisher : Springer Science & Business Media
  • Genre : Science
  • Pages : 440
  • ISBN 13 : 1461594421
  • File Size : 55,55 MB
DOWNLOAD BOOK

Mechanisms of Stimulus—Response Coupling in Platelets by J. Westwick PDF Summary

Book Description: Since its inception the research area of platelet pharmacology has always been a vigorous one and it is a characteristic that new approaches to the understanding of platelet function are rapidly and thoroughly investigated. The intensity of this activity is attri butable, probably, to an appreciation by research workers in the field that a satisfactory therapeutic control of platelet function has yet to be realized. Also that if and when this problem of con trolling platelet function is achieved the benefits to clinical medicine will be immense since platelets are known to be involved in a multiplicity of events coupled within the haemostatic mechanisms and inflammatory responses. Aberrations in the behaviour of plate lets is part of the aetiology of atherosclerosis, myocardial and cerebral infarction and thrombosis. At this point in time, research in platelet function is in a particularly rapid state of flux. The recent findings of research workers active in the field and also workers investigating mechan isms of stimulus response coupling in other cells, have provided interesting insights into the generality of mechanisms involved in the function of responsive cells. One may itemize these developments as the area of cell receptor/ligand interaction, induction of cell ular response by protein phosphorylation and calcium flux. The mech anism of these latter events occurs through the activity of phospho lipase generating transient intermediates. These intermediates may act as ionophores or enzyme activators or may, in the case of eico sanoids, reinforce and make irreversible the cellular response.

Disclaimer: www.yourbookbest.com does not own Mechanisms of Stimulus—Response Coupling in Platelets books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

The Platelets

The Platelets

File Size : 40,40 MB
Total View : 891 Views
DOWNLOAD

The Platelets: Physiology and Pharmacology is a critical review of the basic platelet systems, methodologic critiques, and platelet involvement in major disease

Biochemistry of Platelets

Biochemistry of Platelets

File Size : 19,19 MB
Total View : 3649 Views
DOWNLOAD

Biochemistry of Platelets is a comprehensive review of the biochemistry of platelets, with emphasis on the molecular basis for the various biological processes