Metabolic Basis of Detoxication

Released on by William B. Jakoby
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  • Metabolic Basis of Detoxication Book Detail

  • Author : William B. Jakoby
  • Release Date : 2012-12-02
  • Publisher : Elsevier
  • Genre : Science
  • Pages : 392
  • ISBN 13 : 0323137997
  • File Size : 5,5 MB
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Metabolic Basis of Detoxication by William B. Jakoby PDF Summary

Book Description: Metabolic Basis of Detoxication: Metabolism of Functional Groups considers the possible fates of the relatively circumscribed number of functional groups that xenobiotics bear. An understanding of the possible reactions, and the chemical and biological factors influencing them, will contribute to the overall predictability of the fate of "real" molecules. This approach attempts to knit together the understanding of metabolic pathways with that of the enzymes that catalyze the specific steps. The book contains 18 chapters and begins with a discussion of the biological oxidation of carbon atoms. This is followed by separate chapters on the metabolism of halogenated aliphatic hydrocarbons, aryl halides, heterocyclic rings, alcohols, aldehydes, and ketones. Subsequent chapters cover oxidative processes such as metabolic dealkylations and biological oxidation at nitrogen centers; the reduction of nitro and azo compounds and tertiary amine N-oxides; the oxidation, alkylation, acylation, and glycosylation of mercaptans; epoxide metabolism; and conjugation of phenols. The book aims to inform and interest the pharmacologist and toxicologist concerning the biochemical aspects and to orient the biochemist to the pharmacological insights required in dealing with the metabolism of xenobiotics.

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Metabolic Basis of Detoxication

Metabolic Basis of Detoxication

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Metabolic Basis of Detoxication: Metabolism of Functional Groups considers the possible fates of the relatively circumscribed number of functional groups that x

Enzymatic Basis of Detoxication Volume 1

Enzymatic Basis of Detoxication Volume 1

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Enzymatic Basis of Detoxication, Volume I focuses on the catalytic mechanisms and physiological expression of the enzymes that are involved in the detoxication

Biological Basis of Detoxication

Biological Basis of Detoxication

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Biological Basis of Detoxication focuses on the biological processes involved in detoxication, with emphasis on the biochemistry of the removal of xenobiotics f

Enzymatic Basis of Detoxication Volume 2

Enzymatic Basis of Detoxication Volume 2

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Enzymatic Basis of Detoxication, Volume II, reviews the state of knowledge on foreign compound metabolism at the level of what specific enzymes can do. The book