Metal Compounds in Cancer Therapy

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  • Metal Compounds in Cancer Therapy Book Detail

  • Author : S.P. Fricker
  • Release Date : 2012-12-06
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 269
  • ISBN 13 : 9401112525
  • File Size : 47,47 MB

Metal Compounds in Cancer Therapy by S.P. Fricker PDF Summary

Book Description: The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy. Cisplatin now occupies an important place in the armamentarium of the oncologist due to its effectiveness in the treatment of testicular cancer. A second generation analogue, carbo platin, offers reduced toxicity together with therapeutic activity, which gives it a place in the front-line therapy of genitourinary cancers. These and other successes have encouraged the search for novel metal-based drugs for cancer therapy. Research has shown that metal compounds have potential for activity not only as cytotoxic antitumour agents, but also in areas such as adjuvant therapy, diagnosis and immunotherapy. The aim of this book is to review and describe the major achievements and developments arising from this international research effort. The contributing authors come from labora tories throughout Europe and America and represent the many disci plines characteristic of this research, such as clinical research, pharmacology, tumour biology and inorganic medicinal chemistry.

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Metal Compounds in Cancer Therapy

Metal Compounds in Cancer Therapy

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The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major internat

Metal Compounds in Cancer Therapy

Metal Compounds in Cancer Therapy

File Size : 46,46 MB
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The discovery of the anti-tumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major researc

Metal-based Anticancer Agents

Metal-based Anticancer Agents

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Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compou