Modulating Gene Expression

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RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years,

Bioinformatics in the Era of Post Genomics and Big Data

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Bioinformatics has evolved significantly in the era of post genomics and big data. Huge advancements were made toward storing, handling, mining, comparing, extr

Epigenetic Gene Expression and Regulation

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Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease s

Non-coding RNAs and Epigenetic Regulation of Gene Expression

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Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some

Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning

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When first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level of specificity in contr