Molecular Recognition of DNA Double Helix

Released on by Abhijit Saha
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  • Molecular Recognition of DNA Double Helix Book Detail

  • Author : Abhijit Saha
  • Release Date : 2018-03-22
  • Publisher : Springer
  • Genre : Science
  • Pages : 126
  • ISBN 13 : 9811087466
  • File Size : 97,97 MB
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Molecular Recognition of DNA Double Helix by Abhijit Saha PDF Summary

Book Description: In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using the photochemistry of BrU-labeled DNA. The study began with the design and development of small molecules that can induce pluripotency genes. To deal with the important issue of cell permeability of the original compound, a new analogue of the original with improved gene expression was designed and synthesized. Using the photochemistry of BrU-labeled DNA, crucial biological phenomena such as cooperativity between transcription factors were detected. For the first time, the cooperativity was examined by excess electron transfer assay. DNA was also studied very carefully in order to understand the mechanism of the double-strand break in the UVA micro-irradiation technique. The mechanism of the double strand remained untouched. Nevertheless, the double-strand break mechanism was clearly demonstrated by Hoechst dye, as shown in this book.

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Molecular Recognition of DNA Double Helix

Molecular Recognition of DNA Double Helix

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In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the st

Recent Trends in Molecular Recognition

Recent Trends in Molecular Recognition

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Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a c