New Aspects in Hypertension Adrenoceptors

Released on by M. Middeke
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  • New Aspects in Hypertension Adrenoceptors Book Detail

  • Author : M. Middeke
  • Release Date : 2012-12-06
  • Publisher : Springer Science & Business Media
  • Genre : Medical
  • Pages : 403
  • ISBN 13 : 3642714188
  • File Size : 69,69 MB
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New Aspects in Hypertension Adrenoceptors by M. Middeke PDF Summary

Book Description: This book reports on the current state of knowledge about adreno ceptors and their involvement in the pathogenesis and treatment of high blood pressure. This is a relatively recent and extremely excit ing addition to the field of hypertension research. The development of new analytical procedures, such as radio ligand-binding methods, has made it possible to identify and quantify the adrenoceptors in different tissues and in circulating blood cells. As a consequence, much new and valuable information has been obtained. An under standing of the role of the fJ-adrenoceptor-adenylatecyclase-cAMP system in hypertension is one such product of this new approach. Both review articles and new experimental and clinical data are included in this volume. New aspects of the distribution, identifica tion and regulation, and the chronopharmacology of adrenoceptors, as well as beta blockade, will be highlighted. The clinical contributions concern the normal regulation of the fJ adrenoceptor-adenylatecyclase-cAMP system, and how it is altered in hypertensives as a possible mechanism in the pathogenesis and maintenance of essential hypertension. With this knowledge it is be coming easier to explain the molecular and cellular action behind the familiar role of the sympathico-adrenergic system in the devel opment of hypertension and the mechanism of beta blockade. The vast majority of the data available in this field is confined to periph eral mechanisms, owing to the limited possibilities for investigating the central nervous system under clinical conditions.

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New Aspects in Hypertension Adrenoceptors

New Aspects in Hypertension Adrenoceptors

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This book reports on the current state of knowledge about adreno ceptors and their involvement in the pathogenesis and treatment of high blood pressure. This is

Cellular Aspects of Hypertension

Cellular Aspects of Hypertension

File Size : 93,93 MB
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In the last two decades, investigations at the cellular level have progressively gained ground in the context of hypertension research. This choice of approach