Nuclear Receptors

preview-18
  • Nuclear Receptors Book Detail

  • Author : Mostafa Z. Badr
  • Release Date : 2021-09-28
  • Publisher : Springer Nature
  • Genre : Medical
  • Pages : 676
  • ISBN 13 : 3030783154
  • File Size : 36,36 MB

Nuclear Receptors by Mostafa Z. Badr PDF Summary

Book Description: Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases. This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins. World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters address the various means and consequences of modulating nuclear receptor activity will be presented and discussed. These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.

Disclaimer: www.yourbookbest.com does not own Nuclear Receptors books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Nuclear Receptors

Nuclear Receptors

File Size : 44,44 MB
Total View : 958 Views
DOWNLOAD

Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is p

The Nuclear Receptor FactsBook

The Nuclear Receptor FactsBook

File Size : 90,90 MB
Total View : 5570 Views
DOWNLOAD

The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format a

Nuclear Receptors

Nuclear Receptors

File Size : 24,24 MB
Total View : 9708 Views
DOWNLOAD

The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clin

Nuclear Hormone Receptors

Nuclear Hormone Receptors

File Size : 50,50 MB
Total View : 4335 Views
DOWNLOAD

An overview of the supergene family made up of those nuclear hormone receptors which recognize thyroid and steroid hormones, vitamen D and retinoic acid and whi