Phosphodiesterase Inhibitors

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  • Phosphodiesterase Inhibitors Book Detail

  • Author :
  • Release Date : 1996-08-16
  • Publisher : Elsevier
  • Genre : Science
  • Pages : 247
  • ISBN 13 : 0080538819
  • File Size : 83,83 MB

Phosphodiesterase Inhibitors by PDF Summary

Book Description: Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting. - Utilizes actual testing and research of new PDE inhibitors - Valuable for researchers and students alike

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Phosphodiesterase Inhibitors

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Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, v

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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines t

Phosphodiesterases and Their Inhibitors

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Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, th