Prognostic and Predictive Factors in Autoimmune Connective Tissue Disorders

Released on by Francesca Wanda Rossi
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  • Prognostic and Predictive Factors in Autoimmune Connective Tissue Disorders Book Detail

  • Author : Francesca Wanda Rossi
  • Release Date : 2024-08-30
  • Publisher : Frontiers Media SA
  • Genre : Medical
  • Pages : 147
  • ISBN 13 : 2832553834
  • File Size : 92,92 MB
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Prognostic and Predictive Factors in Autoimmune Connective Tissue Disorders by Francesca Wanda Rossi PDF Summary

Book Description: Autoimmune connective tissue diseases, including systemic lupus erythematosus, Sjögren’s syndrome, systemic sclerosis, dermatomyositis, rheumatoid arthritis, and mixed connective tissue diseases are complex conditions that commonly involve multiple organs and systems. The pathogenesis of many autoimmune diseases is elusive, and the disease course is extremely variable, with indolent or rapidly progressive case subsets. The heterogeneity and patient-to-patient variability of autoimmune connective tissue disease extend to their clinical manifestations, autoantibody profiles, speed of disease progression, the constellation of target organ effects, response to treatment, and survival. Despite the significant advances in diagnosis and treatment achieved in the last decades, due to a relative lack of biomarkers and prognostic indicators, it is still difficult to predict disease progression and prevent the development of severe and life-threatening disease manifestations. In addition, recently, there has been a shift in patient treatment, from treating patients after contracting diseases to personalized medicine, in which diseases are prevented and treated according to individual variability in genes, phenotypical features, environment, and lifestyle for each group of patients. For this reason, this Research Topic aims to promote a greater understanding of the prognostic and predictive factors in connective tissue diseases to predict long-term outcomes and improve the use of tailored treatments.

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