Protein Misfolding, Aggregation and Conformational Diseases

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  • Protein Misfolding, Aggregation and Conformational Diseases Book Detail

  • Author : Vladimir N. Uversky
  • Release Date : 2007-11-24
  • Publisher : Springer Science & Business Media
  • Genre : Science
  • Pages : 450
  • ISBN 13 : 0387259198
  • File Size : 1,1 MB

Protein Misfolding, Aggregation and Conformational Diseases by Vladimir N. Uversky PDF Summary

Book Description: Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. This is the first book to discuss significant achievements in protein structure-function relationships in biochemistry, molecular biology and molecular medicine. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.

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Protein Misfolding and Disease

Protein Misfolding and Disease

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For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation that prote