Proteoforms

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  • Proteoforms Book Detail

  • Author : Xianquan Zhan
  • Release Date : 2020-07-15
  • Publisher : BoD – Books on Demand
  • Genre : Science
  • Pages : 92
  • ISBN 13 : 1838800336
  • File Size : 37,37 MB

Proteoforms by Xianquan Zhan PDF Summary

Book Description: A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia.

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Proteoforms

Proteoforms

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A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofa

Proteoform Identification

Proteoform Identification

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This volume discusses the latest mass spectrometry (MS)-based technologies for proteoform identification, characterization, and quantification. Some of the topi

Proteolytic Signaling in Health and Disease

Proteolytic Signaling in Health and Disease

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In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across hum