Regulation of Endothelial Barrier Function

Released on by Sarah Y. Yuan
preview-18

  • Regulation of Endothelial Barrier Function Book Detail

  • Author : Sarah Y. Yuan
  • Release Date : 2011-02-01
  • Publisher : Biota Publishing
  • Genre : Medical
  • Pages : 160
  • ISBN 13 : 1615041214
  • File Size : 77,77 MB
DOWNLOAD BOOK

Regulation of Endothelial Barrier Function by Sarah Y. Yuan PDF Summary

Book Description: The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the vascular wall and surrounding extravascular tissues. In addition to regulating blood delivery and perfusion, a major function of vascular endothelia, especially those in exchange microvessels (capillaries and postcapillary venules), is to provide a semipermeable barrier that controls blood–tissue exchange of fluids, nutrients, and metabolic wastes while preventing pathogens or harmful materials in the circulation from entering into tissues. During host defense against infection or tissue injury, endothelial barrier dysfunction occurs as a consequence as well as cause of inflammatory responses. Plasma leakage disturbs fluid homeostasis and impairs tissue oxygenation, a pathophysiological process contributing to multiple organ dysfunction associated with trauma, infection, metabolic disorder, and other forms of disease. In this book, we provide an updated overview of microvascular endothelial barrier structure and function in health and disease. The discussion is initiated with the basic physiological principles of fluid and solute transport across microvascular endothelium, followed by detailed information on endothelial cell–cell and cell–matrix interactions and the experimental techniques that are employed to measure endothelial permeability. Further discussion focuses on the signaling and molecular mechanisms of endothelial barrier responses to various stimulations or drugs, as well as their relevance to several common clinical conditions. Taken together, this book provides a comprehensive analysis of microvascular endothelial cell and molecular pathophysiology. Such information will assist scientists and clinicians in advanced basic and clinical research for improved health care.

Disclaimer: www.yourbookbest.com does not own Regulation of Endothelial Barrier Function books pdf, neither created or scanned. We just provide the link that is already available on the internet, public domain and in Google Drive. If any way it violates the law or has any issues, then kindly mail us via contact us page to request the removal of the link.

Regulation of Endothelial Barrier Function

Regulation of Endothelial Barrier Function

File Size : 12,12 MB
Total View : 6633 Views
DOWNLOAD

The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the

Regulation of Endothelial Barrier Function

Regulation of Endothelial Barrier Function

File Size : 59,59 MB
Total View : 2021 Views
DOWNLOAD

The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the

Inflammation and the Microcirculation

Inflammation and the Microcirculation

File Size : 92,92 MB
Total View : 558 Views
DOWNLOAD

The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillari

The Endothelium

The Endothelium

File Size : 70,70 MB
Total View : 1481 Views
DOWNLOAD

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphati

Capillary Fluid Exchange

Capillary Fluid Exchange

File Size : 84,84 MB
Total View : 9281 Views
DOWNLOAD

The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular wa