RNA Damage and Repair

Released on by Ioly Kotta-Loizou
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  • RNA Damage and Repair Book Detail

  • Author : Ioly Kotta-Loizou
  • Release Date : 2021-07-04
  • Publisher : Springer Nature
  • Genre : Science
  • Pages : 180
  • ISBN 13 : 3030765717
  • File Size : 46,46 MB
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RNA Damage and Repair by Ioly Kotta-Loizou PDF Summary

Book Description: Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems). Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.

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RNA Damage and Repair

RNA Damage and Repair

File Size : 42,42 MB
Total View : 9297 Views
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Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DN

RNA Damage and Repair

RNA Damage and Repair

File Size : 42,42 MB
Total View : 9967 Views
DOWNLOAD

Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DN

DNA Damage and Repair

DNA Damage and Repair

File Size : 44,44 MB
Total View : 8362 Views
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Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer.