Signaling by Receptor Tyrosine Kinases

Released on by Joseph Schlessinger
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  • Signaling by Receptor Tyrosine Kinases Book Detail

  • Author : Joseph Schlessinger
  • Release Date : 2014
  • Publisher :
  • Genre : Science
  • Pages : 0
  • ISBN 13 : 9781936113330
  • File Size : 20,20 MB
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Signaling by Receptor Tyrosine Kinases by Joseph Schlessinger PDF Summary

Book Description: Receptor tyrosine kinases are cell-surface receptors that respond to numerous hormones and growth factors, including insulin, insulin-like growth factors, epidermal growth factor, and nerve growth factor. They activate highly conserved intracellular signaling pathways that regulate cell proliferation, differentiation, and metabolism, playing essential roles in developing and adult animals. This book examines the nature of these receptors and their ligands, the molecular mechanisms that they regulate within cells, and the roles of the receptors in normal physiology and control of embryogenesis. It also discusses how dysfunction of these mechanisms can contribute to cancer and other diseases.

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Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases

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Receptor tyrosine kinases are cell-surface receptors that respond to numerous hormones and growth factors, including insulin, insulin-like growth factors, epide