The HLA FactsBook

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  • The HLA FactsBook Book Detail

  • Author : Steven G.E. Marsh
  • Release Date : 1999-12-13
  • Publisher : Elsevier
  • Genre : Medical
  • Pages : 413
  • ISBN 13 : 0080542506
  • File Size : 68,68 MB

The HLA FactsBook by Steven G.E. Marsh PDF Summary

Book Description: The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references

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The HLA FactsBook

The HLA FactsBook

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The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus

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Immunobiology of HLA

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The Tenth International Histocompatibility Workshop of this work, and Fran Berman for her help in preparing component concerning T-cell recognition of HLA class

MHC Protocols

MHC Protocols

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The aim of MHC Protocols is to document protocols that can be used for the analysis of genetic variation within the human major histocompatibility complex (MHC;