Synthesis and Characterization of Glycosides

Released on by Marco Brito-Arias
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  • Synthesis and Characterization of Glycosides Book Detail

  • Author : Marco Brito-Arias
  • Release Date : 2022-04-22
  • Publisher : Springer Nature
  • Genre : Science
  • Pages : 543
  • ISBN 13 : 3030978540
  • File Size : 79,79 MB
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Synthesis and Characterization of Glycosides by Marco Brito-Arias PDF Summary

Book Description: This third edition is a comprehensive and extended study about the best known approaches for preparing the main types of glycosides, covering the classic and more recent glycosylation reactions used for preparing simple and challenging glycosides currently used as potent antiviral and antineoplastic drugs, or fluorogenic substrates used for enzymatic detection in cell biology. Besides, this new edition provides more examples of the glycosidic methodologies followed for preparing complex glycoconjugates such as glycoproteins and glycosphingolipids and gangliosides used as adjuvants or as synthetic vaccines candidates. Also, additional mechanistic evidence is presented for better understanding of the glycosylation reaction, trying to identify the variables mainly depending on protecting and leaving groups, as well as catalyst and reaction condition which altogether directs the anomeric stereo control. A chapter on the glycoside hydrolysis is included in view of the increasing interest in the use of biomass as a natural and renewable source for obtaining important intermediates or products used in food or valuable materials. The author includes information in the characterization of glycosides section with the aim of giving additional tools for the structural assignment through NMR, X-Ray and mass spectra techniques.

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C-Glycoside Synthesis

C-Glycoside Synthesis

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This book examines methods particularly well suited for either a- or b-C-glycoside formation. It helps field workers quickly select the best method for synthesi