Targeted Protein Degradation

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  • Targeted Protein Degradation Book Detail

  • Author : Angela M. Cacace
  • Release Date : 2021-08-26
  • Publisher : Humana
  • Genre : Science
  • Pages : 351
  • ISBN 13 : 9781071616642
  • File Size : 13,13 MB

Targeted Protein Degradation by Angela M. Cacace PDF Summary

Book Description: This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

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Targeted Protein Degradation

Targeted Protein Degradation

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This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteoly

Targeted Protein Degradation

Targeted Protein Degradation

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Targeted Protein Degradation, Volume 680 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting c

Inducing Targeted Protein Degradation

Inducing Targeted Protein Degradation

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Enables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation Since the introduction of th