The Picornaviruses

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  • The Picornaviruses Book Detail

  • Author : Ellie Ehrenfeld
  • Release Date : 2010-09-15
  • Publisher : American Society for Microbiology Press
  • Genre : Science
  • Pages : 1039
  • ISBN 13 : 1555816037
  • File Size : 47,47 MB

The Picornaviruses by Ellie Ehrenfeld PDF Summary

Book Description: A springboard for developing new approaches to understanding, preventing, and treating picornaviral diseases. • Examines the most current breakthroughs as well as the challenges that lie ahead in picornavirus research; encapsulates current knowledge of the molecular biology, evolution, and pathogenesis of this large family of viruses; and, examines the diseases that these viruses cause and the latest vaccines and antiviral drugs to prevent and control those diseases. • Explores the structural and mechanistic bases of picornavirus replication, highlighting new insights about the host cell interactions needed for virus growth; and, illustrates how the regular occurrence of mutations, typical of viruses with RNA as genetic material, generates the quasispecies dynamics that underlie viral fitness. • Focuses on picornaviruses that cause disease, examining pathogenicity and innate and acquired immune responses against infection as well as the latest vaccine and antiviral drug strategies.

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